Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation
HOCl dose dependently exhibited broad spectrum anti-viral effects against adenovirus, hepatitis B, Japanese encephalitis, and rotavirus.
Author/Source: Dianty R et al., 2023, Frontiers in Microbiology
No discernible effects were seen on viral RNA. HOCl substantially reduced infectivity of SARS-CoV-2 virus. HOCl was found to oxidise and aggregate spike and nuclear proteins, and disrupted binding of SARS-CoV-2 to human ACE2.
The authors conclude by stating that "the promising attributes of (HOCl) as a potential antiviral agent for airborne and droplet transmitted pathogens, coupled with it cost effectiveness and absence of observed metal corrosion or chemical harm during environmental application, suggest its significance as a valuable agent in alleviating the global pandemic impact".